Negative Pressure Wound Therapy With Instillation for Treatment of

Hidradenitis Suppurativa (HIDRA)

 

ID number# NCT04325607

 

Recruitment Status: Recruiting as of August 2020 

Estimated Study Completion Date: November 2022

HS Connect listed this in August 2020

 

Sponsor: Royal Free Hospital NHS Foundation Trust

Collaborator: KCI Europe Holding B.V.Information provided by (Responsible Party): Royal Free Hospital NHS Foundation Trust

 

Brief Summary:

 

The current surgical management for severe Hidradenitis suppurativa (HS) involves wide excision of affected skin, resulting in a large soft tissue defect. The soft tissue defect will then be managed with Negative Pressure Wound Therapy (NPWT) to promote healthy granulation tissue formation for wound coverage with Split skin graft (SSG). This long interval between excision and reconstruction could result in long in-patient stay, increased risk of hospital acquired infection and reduced patients' quality of life.

 

The investigators wish to evaluate the use of Negative Pressure Wound Therapy with instillation (NPWTi), which has potential to allow early wound coverage with SSG, as an alternative to the current standard of care. The investigators hypothesise that NPWTi reduces bacterial load on the wound and allows early wound coverage hence improves patient satisfaction and reduces cost and length of hospital stay. The investigators plan to study up to 44 patients in total.

 

Please link for complete details:

 

https://clinicaltrials.gov/ct2/show/NCT04325607

 

Location:

United Kingdom

Royal Free NHS Foundation Trust Hospital London

London, United Kingdom, NW3 2QG

 

Contact Information: Muholan Kanapathy, PhD 020 7794 0500

email:

 

Contact: Ibby Younis Principal Investigator: Ibby Younis, Phd

020 7794 0500 ext 35556    Email: ibbyyounis@nhs.net